Duane Reade · Manhattan, NY

Duane Reade – Main Street

425 MAIN STREET

Manhattan, NY 10044

Address

425 Main Street, New York, NY 10044

Phone

+1 646-521-2260

Opening hours

Hours may differ on public holidays.

Website

Coordinates

40.758810, -73.953357

This listing is based on OpenStreetMap data (updated 2026-10-06). Something wrong? Fix it on OpenStreetMap or let us know.

Frequently asked questions

Where is Duane Reade – Main Street?

Duane Reade – Main Street is located at 425 Main Street, New York, NY 10044. Use “Get directions” to start a route from where you are.

What is the phone number of Duane Reade – Main Street?

The listed phone number is +1 646-521-2260.

What are the opening hours of Duane Reade – Main Street?

Recorded opening hours: Monday – Friday 9 AM–8 PM; Saturday 9 AM–6 PM; Sunday 10 AM–5 PM. Hours may differ on holidays.